Department of Biomedical Engineering

BME 4580/5560: Biomedical Engineering Optics

Fall 2005 (M-W 14:40-15:55)

Catalog Description

Introduction to physical and geometrical optics of biomedical optical devices. Design of optical microscopes, endoscopes, fiber optic delivery systems, spectrometers, fluorometers, and cytometers.

Prerequisites: Calculus, Differential Equations, Chemistry, and Physics.

Major Topics:

Physics of optics, tissue optics, light tissue Interaction, optical spectroscopy, fiber optics, clinical applications

Textbook(s): None

References:

• Optics (4th edition) - by Hecht, Addison Wesley Publishing Co., 1987
• Introduction to Biophotonics – by Paras N. Prasad, John Wiley & Sons Inc., 2003
• Optical-Thermal Response of Laser Irradiated Tissue – by Welch and Van Gemert, Plenum, Press, New York and London, 1995.
• Introduction to Modern Optics (2nd edition) – by Fowles, Dover Publication Inc., New York, 1989.

Class hours:

Lecture: 3 hrs (M-W 2:30-4:00 pm)

Office hours:

4:00 pm - 5:00 pm (Monday and Wednesday).

Contact Information

Wei-Chiang Lin

Office: EC 2673

Emai: wclin@fiu.edu

Tel: 305-348-6112

Course outcomes:

By the end of the course the student should he able to:

• Learn and apply the physics behind biomedical optics
• Apply the fundamentals of optics principles to tissue-related Science and/or biological system
• Design of optics-based instruments for applications such as diagnostics, sensing and/or therapeutics
• Apply mathematical tools in solving optics-based engineering problems;
• Develop a research proposal

Policy regarding student misconduct

Students at Florida International University are expected to adhere to the highest standards of integrity in every aspect of their fives. Honesty in academic matters is part of this obligation. Academic integrity is the adherence to those special values regarding life and work in an academic community. Any act or omission by a student which violates this concept of academic integrity shall be defined as academic misconduct and shall be subject to the procedures and penalties established by the university. Students violating academic integrity will receive a failing grade for the course and the incident will be forwarded to Student Academic Affairs.

Academic misconduct includes, but is not limited to:

· Copying homework

· Copying work on exams either in-class or take-home

· Copying of projects and/or

· Plagiarism (i.e. using others' ideas and words without clearly acknowledging the source of that information. This includes, but is not limited to, (i) internet, (ii) textbooks, (iii) journals, and/or (iv) any other material that is not your own work)

Assignments

Homeworks (biweekly, 20%)

Midterm (25%)

Final Examination (take-home 25%)

Semester Project: Research Proposal (30%)

Major topics:

I. How to write a good research proposal (semester project discussion)

II. Introduction of biomedical optics

III. Light

a. EM Theory

b. Index of refraction

c. Polarization

IV. Optical components

a. Lenses

b. Optical fibers

c. Filters

d. Gratings

V. Light-Material interaction

a. Optical properties

b. Light propagation

i. Theories

ii. Modeling

VI. Optical spectroscopy

a. Elastic scattering spectroscopy

b. Absorption spectroscopy

c. Fluorescence Spectroscopy

d. Roman Spectroscopy

e. Instrumentation

VII. Optical imaging

VIII. Clinical Optical Apparatus