Instructor:                 James Byrne                  

Office:                         EAS 2612

Phone  348-1409

Email:                         james.byrne@fiu.edu

Textbook:                     Handouts will be provided

Class Description:              

Biomedical Engineering Lab 1 incorporates the implementation of  experimentsof experiments in biomechanics and biomedical fluid dynamics. Topics include:

1. Measurement of blood viscosity
2.  Laser Doppler velocity meter theory and flow measurements in vitro
3. Soft and hard tissue mechanics
4. Mechanics and materials for artificial organs and implants
5. A Windkessel model is compared to performance of a Vivitro Cardiovascular                                                               left ventricle and circulatory system simulator

Course Objectives:  By the end of this course students should be able to

1.      Conduct experiments involving transport, mechanics and instrumentation.

2.      Apply multivariable calculus and differential equations to the design and execution of experiments.

3.      Develop and demonstrate an ability to make measurements on and interpret data from living systems.

4.      Develop skill in the use of modern engineering tools

5.      Analyze and interpret data.

6.      Address problems associated with the interaction between living and non-living materials and systems.

7.      Utilize analytical and experimental methods and modern computer technology for decision-making and to solve realistic biomedical engineering problems.

8.      Work effectively with others in a team while simultaneously maintaining independent and creative thought.

9.      Communicate effectively and to articulate technical matters using verbal, written, and graphic techniques.

   Points Distribution:

  Report Grading Criteria:     

Technical Content                                60%

            Figures, Equations, Tables                   30%

            Spelling and Grammar                          5%

            Style (impress me points)                      5%  

Course Grading Criteria:

           Experimental Summary Reports           70%

            Short Engineering Report                     30%

Tentative Course Outline:

Completion of FIU’s online laboratory safety training will be required of all students.

The courses completed shall be:

1.        1004 Laboratory Safety

2.        Hazard Communication

3.        1003 Bloodborne Pathogens Exposure Control

4.        1008 FIU Hazardous Waste Management Training

5.        Research Involving Animals

Items 1 through 4 are accessible through http://www.fiu.edu/~ehs/safety_training/training_course_list.htm

Item 5 is accessible through http://www.dsrt.fiu.edu/animalsubjects/animal_subjects.htm

All students shall earn a certificate in each before they may participate in laboratory experiments. Evidence of completion shall be a print out from the training website showing mastery of the course material.  A certificate will be mailed to me by EH&S or DSRT after completion of the courses.  I will copy the certificate for my files and deliver the original to the students.  This certificate may be used may be used at this or other institutions as evidence of lab safety training.

 Five laboratory exercises will be performed from the following list:

Blood Rheology

·         Determination of hematocrit.

·         Viscometry of blood with Brookfield DV II+.

These experiments provide experience with transport and fluid mechanics, instrumentation on living tissue (animal blood).

Objectives met: 1, 3, 5, 6, 8, 9

Laser Doppler Velocimetry

 ·         Biopac fiber optic LDV system theory and operation.

·         Laminar Flow in a rectangular duct, theory.

·         Laminar flow measurements in a rectangular duct using LDV.

This laboratory provides experience with transport and optical instrumentation

Objectives met: 1, 2, 4, 5, 6, 7, 8,

Soft Tissue Mechanics

·        Elastic Modulus and ultimate tensile strength of animal tendon at different strain rates.

·        Measure Viscoelastic properties of cartilage.

·          Fit Viscoelastic Voight or Kelvin Model to Data via MATLAB©

This lab provides experience with the Enduratec ELF 3200 Tensile Test Machine.

Objectives Met:  All of the objectives of the course are met in the course of this laboratory exercise.

Hard Tissue Mechanics

·       Determine anisotropy of some mechanical properties of cortical bone.

·         Measure Elastic Modulus and ultimate strength of cortical bone in compression. In 3 axes

This lab provides experience with the Enduratec ELF 3200 Tensile Test Machine.

Objectives Met:  1,3,4,5,6,8,9

Modeling Cardiovascular Fluid Dynamics

·        Numerical modeling of windkessel, valve flow and pressure measurements.

·         Experimental modeling of windkessel model using Vivitro Systems. Left Heart Simulator

Objectives Met:  All of the objectives of the course are met in the course of this laboratory exercise.